差し障る

さしさわる
to hinder
to adversely affect

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さしさわる【差し障る】

〔支障となる〕 obstruct; hinder; be a hindrance 《to…》; be bad 《for…》; adversely affect.

●からだに差し障る have a bad effect on one's health

・勉強に差し障る hinder [be a hindrance to] study

・就職に差し障る badly affect employment opportunity.